The goal of polymeric micelle technology is to enhance solublization of water insoluble drugs to facilitate formulation of therapeutically more effective products.
Samyang’s proprietary biodegradable polymers such as poly(ethylene glycol)-poly(lactic acid) block copolymers have specific functionality. These polymers have strong potential for the development of self-forming nanometer-size(<50nm) micelle particles which can be administered directly to the specific sites and release the incorporated or entrapped drug in a sustained manner. Samyang’s proprietary polymeric micelle technology is being evaluated as a potential formulation strategy for systemic or local delivery of highly water insoluble drugs.
Testing to date has demonstrated significant pharmaceutical and biological advantages for polymeric micelle formulations as compared to standard preparations. The technology enables development of pharmaceutically acceptable formulations with enhanced stability and improved bioavailability of highly water insoluble drugs. Additional potential of the technology may be realized for manipulating pharmacokinetic parameters and distribution of drug in tissues. |